CAVER Analyst software free download tool for analysis and visualization of tunnels and channels in protein structures in computational chemistry and biochemistry. Tunnels are void pathways leading from a cavity buried in a protein core to the surrounding solvent. Unlike tunnels, channels lead through the protein structure and their both endings are opened to the surrounding solvent. Studying of these pathways is highly important for drug design and molecular enzymology.
CAVER Analyst provides rapid, accurate and fully automated calculation of tunnels and channels in static and dynamic structures. The molecules amendable to analysis of CAVER include proteins, nucleic acids, or inorganic materials. The software is available as CAVER 3.0 command-line version, CAVER 3.0 PyMol plugin or graphical application CAVER Analyst.