Molecular Docking Course with MOE 2023 and Determining Protein-Ligand Interactions Using Molecular Operating Environment (MOE) software. This course offers a comprehensive exploration of the intricate world of molecular docking, commencing with an in-depth overview of key terminologies and step-by-step docking procedures.
Through engaging visuals and interactive content, participants will master the essential building blocks required to conduct successful molecular docking studies. Central to the course is an immersive exploration of molecular docking using the Molecular Operating Environment (MOE), a prominent software platform in the field. Participants will embark on a guided journey through each phase of docking, backed by captivating visuals and illustrative videos.
What you’ll learn
- Participants will gain a solid understanding of the fundamental concepts of molecular docking, including ligands, proteins, binding sites, and interactions.
- Participants will be able to explain the concept of binding affinities and how they relate to ligand-protein interactions.
- Participants will explore various real-world applications of molecular docking in fields like drug discovery and protein engineering.
- Participants will learn how to prepare protein and ligand structures for docking simulations.
- Participants will be able to set up docking simulations, define binding sites, and configure parameters for docking runs.
- Participants will become proficient in using the Molecular Operating Environment (MOE) software for performing molecular docking simulations.
- Participants will acquire skills in interpreting docking results, analyzing binding poses, and evaluating ligand-protein interactions.
- Participants will understand the limitations of molecular docking methods and when alternative approaches might be more suitable.
Who this course is for
- Biology and Chemistry Students
- Researchers and Scientists
- Pharmaceutical Industry Professionals
- Educators and Instructors
- Researchers in Structural Biology
- Graduates of Introductory Bioinformatics Courses
- Students of Biochemistry and Molecular Biology
- Anyone Interested in Drug Discovery
- Anyone Interested in Molecular Docking
- Section 1: Introduction to the Course
- Lecture 1 Course Outline
- Section 2: Theoretical Framework for Molecular Docking
- Lecture 2 Introduction to Molecular Docking
- Lecture 3 Basic Terminologies
- Lecture 4 Key Steps in Molecular Docking
- Section 3: Mid Term
- Section 4: Performing Molecular Docking Using MOE
- Lecture 5 Target Selection and Preparation (Part 1)
- Lecture 6 Target Selection and Preparation (Part 2)
- Lecture 7 Ligand Selection and Preparation
- Lecture 8 Running Docking Simulation
- Lecture 9 Analyzing Docking Results
- Lecture 10 Visualizing 2D Interactions Using BIOVIA Discovery Studio
- Lecture 11 Limitations of Molecular Docking
- Movie quality: MP4 | Video: h264, 1280 × 720
- Audio quality: Audio: AAC, 44.1 KHz, 2 Ch
- Movie duration: 1h 14m
- Number of lessons: 11 lectures
- Language: English
- Compressed file size: 600 MB