Download Introductory Mass Spectrometry Second Edition
Mass spectrometry has been an important analytical method for investigating the structures of organic molecules for over five decades. Even when only a small sample is available, it can provide valuable structural information. In particular, electron ionization produces a characteristic mass spectrum containing a series of peaks that can help chemists determine the structure and identity of an unknown compound. Introductory Mass Spectrometry, Second Edition is designed to help students and chemists understand these spectral patterns and use them to address practical structural identification problems.
This revised edition incorporates modern mass spectrometric methods as well as updated approaches to data analysis. It first introduces the fundamental principles of mass spectrometry and the design and operation of the instrumentation. The discussion then follows the sequence of events that take place inside the mass spectrometer after ionization. A major feature of the book is its extensive collection of mass spectra, covering a broad range of organic compounds. Particular attention is given to the connection between fragmentation behavior, familiar chemical reactions, and molecular structure. The book also examines softer ionization methods, which are especially useful for obtaining reliable molecular-weight information.
The text explains how electron-ionization spectra can be interpreted by relating the positions and intensities of spectral peaks to molecular structure. It also explores high-resolution mass spectrometry and accurate mass measurements for establishing the elemental composition of ions and assisting in the identification of unknown compounds. In addition, readers are introduced to newer analytical approaches that expand the application of mass spectrometry to larger molecules and compounds with greater polarity. Numerous examples and practice problems drawn from different areas of organic chemistry reinforce the concepts and help readers apply mass-spectrometric principles to real structural analysis.
- Author (s): Stephen Shrader
- Year of publication: 2017
- Publisher: CRC Press
- Language: English
- ISBN: 9781466595842, 1466595841, 9781466595859, 1138402494, 9781138402492
- Number of pages: 188 pages
- Book format: PDF
- File size: 3 MB
